Azicine 250 mg

Rx

Indications

• Azicine 250 mg is indicated for the treatment of infections:
• Upper respiratory tract infections: Ear, nose and throat infections like sinusitis, tonsillitis, otitis media.
• Lower respiratory tract infections: Pneumonias, acute bronchitis.
• Skin and soft tissue infections: Furunculosis, pyoderma, impetigo due to Staphylococcus aureus.
• Sexually transmitted diseases: Urethritis and cervicitis, non-gonococcal urinary tract infections and pelvises.

Dosage

Adults

• Upper and lower respiratory tract infections, skin and soft-tissue infections: Initial dosage is 500 mg as a single dose on the first day and followed by 250 mg once daily for 4 days.
• Sexually transmitted diseases: 1 g as a single dose.

Children over 6 months of age

• One single dose of 10 mg/kg/day for 3 days.

Usage

• Azicine 250 mg is administered orally, dissolved in warm water, administered at least 1 hour before or 2 hours after a meal.

Known hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic, or to any of the excipients.

• Gastrointestinal disturbances in origin with nausea, abdominal discomfort (pain/ cramps), vomiting, flatulence, diarrhea, and loose stools.
• Higher doses were used for prolonged periods of time, reversible hearing impairment was seen in some patients.
• Serious hypersensitivity reactions, including angioedema, anaphylaxis, and dermatologic reactions, have occurred rarely in patients receiving azithromycin.

• The use of the drug is not recommended in children under 6 months.
• The drug should be used with caution in patients with impaired hepatic function, renal impairment (glomerular filtration rates less than 10 ml/minute).
• Prolonged cardiac repolarization and QT interval with risk of cardiac arrhythmia and torsades de pointes has been reported.
• Azicine 250 mg should be used only for the treatment or prevention of infections proven or strongly suspected to be caused by susceptible bacteria.
• Azicine 250 mg should be used during pregnancy only when clearly needed and used with caution in nursing women.
• Patients should be aware of how they react to drug before driving or operating machinery.