Partamol Tab.

OTC

Indications

• For treatment of mild to moderate pain and fever, especially in patients in whom salicylates are contraindicated or not tolerated.
• The drug is most effective in relieving low intensity pain of non-visceral origin.

Dosage:

• Adults and children > 12 years of age:
  500 mg – 1000 mg every 4 – 6 hours as necessary, but should not exceed 4 g daily.
• Children 6 – 12 years of age:
  250 mg – 500 mg every 4 – 6 hours when necessary up to a maximum of 4 doses in 24 hours.
• Use of this drug should not be recommended for children under 6 years old.
• Paracetamol should not be used for self-medication of pain for longer than 10 days in adults or 5 days in children.
• Paracetamol should not be used for self-medication of marker fever (greater than 39.5^oC), fever persisting longer 3 days, or recurrent fever.

Usage

• Partamol Tab. is administered orally.

• Patients with known hypersensitivity to paracetamol or to any of the ingredients.
• Severe hepatic impairment.

• Serious skin reactions such as Stevens-Johnson syndrome, Lyell’s syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis occur rarely, but potentially fatal. If patients get a rash or other skin manifestations, to stop taking drug and notify your physicians.

Uncommon

• Rash, nausea, vomiting,
• Blood dyscrasias (neutropenia, pancytopenia, leukopenia), anemia,
• Nephropathy, nephrotoxicity with chronic abuse.

Rare

• Stevens-Johnson syndrome, toxic epidermal necrolysis, Lyell’s syndrome, acute generalized exanthematous pustulosis,
• Hypersensitivity reactions.

• Paracetamol should be used with caution in patients with preexisting anemia, since cyanosis may not be apparent despite dangerously high blood concentrations of methemoglobin.
• Excessive intake of alcohol may increase the risk of paracetamol induced hepatotoxicity; avoid or limit alcohol intake.
• Caution is recommended when giving to patients with hepatic or renal impairment.
• The physicians need to warn the patients of the signs of serious skin reactions known as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) or Lyell’s syndrome, acute generalized exanthematous pustulosis (AGEP).
• Paracetamol should be only used in pregnant women when clearly needed.
• There is no evidence that paracetamol affects the ability to drive or to operate machinery.