Bicimax

OTC

Indications

• Supplementation of deficiencies of the vitamins B complex, vitamin C, calcium and magnesium: e.g., prolonged stress, prolonged infection and fever, intestinal diseases, gastrectomy, alcohol abuse…

Dosage

• Bicimax is used for adults and children over 15 years old.
• 1 effervescent tablet daily or as prescribed by your doctor.

Usage

• Bicimax is administered orally. The effervescent tablet is dissolved in about 200 ml of water and use immediately.

• Hypersensitivity to any of the ingredients.
• Patients with allergy, severe renal insufficiency, nephrolithiasis, malignant tumor, hypercalcaemia, severe hypercalciuria calci-lithiasis and renal calculi.
• Large dose of vitamin B₃ should be avoided in patients with severe liver disease, active peptic ulcer, arterial hemorrhaging, severe hypotension.
• Large dose of vitamin C should be avoided in patients with glucose-6-phosphate dehydrogenase deficiency, history of nephrolithiasis, hyperoxaluria, thalassemia.

• Long-term use of large doses of vitamin B₆ is associated with the development of severe peripheral neuropathy.
• Gastrointestinal disturbances associated with high vitamin C intake: diarrhea, nausea, abdominal cramps, transient colic, and flatulent distension.
• Calcium carbonate may occasionally cause constipation. High doses or prolonged use may lead to gastric hypersecretion and acid rebound.
• Ingestion of magnesium salts may cause gastro-intestinal irritation and watery diarrhea.

• Large doses of vitamin B₃ should be administered with caution to patients with a history of peptic ulcer disease, gallbladder disease or a history of jaundice or liver disease, diabetes mellitus, gout, gout arthritis or allergy.
• Ingestion of large doses of the vitamin C during pregnancy has resulted in scurvy in neonates.
• Hyperoxaluria may occur when using large doses of vitamin C. Vitamin C may cause acidification of the urine, precipitation of urate, cystine, or oxalate stones, or drugs in the urinary tract.
• Calcium salts should be given cautiously to patients with renal impairment, or diseases associated with hypercalcaemia such as sarcoidosis and some malignancies. In addition, they should generally be avoided in patients with calcium renal calculi, or a history of renal calculi.
• Oral magnesium salts should be used cautiously in patients with renal impairment.
• Bicimax should not be administered during pregnancy/lactation.
• Bicimax causes none effect on ability to drive and use machines.

• Vitamin B1 (thiamine mononitrate) ………………………………….15.00 mg
• Vitamin B2 (Riboflavin Sodium Phosphate) ………………………..15.00 mg
• Vitamin B6 (pyridoxine hydrochloride) (as pyridoxine 8.23 mg) ….10.00 mg
• Vitamin B12 (Cyanocobalamin) ……………………………………….0.01 mg
• Vitamin B3 (Nicotinamide) ……………………………………………50.00 mg
• Vitamin B5 (calcium pantothenate) ………………………………….23.00 mg
• Vitamin B8 (Biotin) ………………………………………………………0.15 mg
• Vitamin C (Ascorbic Acid) ………………………………………….1000.00 mg
• Calcium (as Calcium Carbonate) …………………………………..100.00 mg
• Magnesium (as Magnesium Hydroxide) …………………………..100.00 mg