Etoricoxib 120 mg

Rx

Indications

Indicated in adults and adolescents 16 years of age and older for:

• The symptomatic relief of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and acute gouty arthritis.
• The short-term treatment of moderate pain postoperative dental surgery pain.

Dosage

• Osteoarthritis:
  30 mg once daily.
  60 mg once daily may be provided in some patients.
  Should not exceed 60 mg daily.
• Rheumatoid arthritis/ankylosing spondylitis:
  60 mg once daily.
  90 mg once daily may be provided in some patients.
  Should not exceed 90 mg daily.
• Acute gouty arthritis:
  120 mg once daily, maximum of 8 days.
  Should not exceed 120 mg daily.
• Postoperative dental surgery pain:
  90 mg once daily, maximum of 3 days.
  Should not exceed 90 mg daily.

Administration

• Administered orally whole tablet with much water,
• And may be taken with or without food. The onset of the effect of the medicinal product may be faster when etoricoxib is administered without food.

• Hypersensitivity to the etoricoxib or to any of the excipients.
• Active peptic ulceration or active gastro-intestinal (GI) bleeding.
• Patients who, after taking acetylsalicylic acid or NSAIDs including cyclooxygenase-2 (COX-2) inhibitors, experience bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or allergic-type reactions.
• Severe hepatic and renal dysfunction.
• Inflammatory bowel disease.
• Congestive heart failure (NYHA II-IV).
• Patients with hypertension whose blood pressure is persistently elevated above 140/90 mmHg and has not been adequately controlled.
• Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease.
• Pregnancy and lactation.
• Children and adolescents under 16 years of age.

Possible adverse reactions:

• Digestive disorders (bloating, nausea, diarrhea, stomach pain).
• Edema, fluid retention, hypertension.
• Dizziness, headache, weakness.

• Etoricoxib may mask fever and other signs of inflammation.
• Caution should be exercised when combining etoricoxib with warfarin or other oral anticoagulants.
• Avoid using etoricoxib in women who are trying to become pregnant.
• Do not use etoricoxib in pregnant or breastfeeding women.
• Patients who experience dizziness, vertigo or somnolence while taking etoricoxib should refrain from driving or operating machinery.