Spirastad Plus

Rx

Indications

• Treatment of buccodental infection (dental abscesses, phlegmons, infections of salivary glands).
• Preventive treatment of local infections after stomatological and dental surgery.

Dosage

• Adults: 4 to 6 tablets daily in 2 or 3 doses during meals.
• Children from 6 to 10 years old: 2 tablets daily in 2 doses during meals.
• Children from 10 to 15 years old: 3 tablets daily in 3 doses during meals.

Usage

• Spirastad Plus is administered orally.

Patients with known hypersensitivity to spiramycin or any of macrolide antibiotics, metronidazole, other nitro-imidazole derivatives or to any ingredient in the formulation.

Common

• Nausea, vomiting, diarrhea, indigestion, anorexia, abdominal discomfort;
• Vertigo, headache.

Uncommon

• Fatigue, epistaxis, sweating, heaviness in the chest;
• Transient paresthesias, dysesthesia, giddiness, pain, muscular and knuckle stiffness;
• Acute colitis;
• Exanthema, urticaria, rash;
• Leukopenia.

• Spirastad Plus must be discontinued if at the start of treatment, patients experience generalized erythema and pustules accompanied by fever. This case must be contraindicated re-administered with spiramycin.
• Spirastad Plus should be used cautiously in patients with hepatic dysfunction, heart disease, arrhythmia (including people tend to prolong the QT interval); the elderly.
• Mild disulfiram-like reactions including flushing, headaches, nausea, vomiting, abdominal cramps and sweating may occur.
• With the high doses required against anaerobe infections, and against amoebiasis and giardiasis, blood dyscrasia and active neurologic diseases can occur.
• Taking metronidazole may have infection Candida in the mouth, vagina or intestines. If super-infection occurs, appropriated treatment is used.
• It is advisable to avoid taking Spirastad Plus during pregnancy. If you discover that you are pregnant while you are taking this drug, consult your physician should continue taking this drug or not. Taking Spirastad Plus should be avoided during lactation or mothers should discontinue breast-feeding during Spirastad Plus
• Patients should be aware of how they react to drug before driving or operating machinery. Spirastad Plus has the potential for drowsiness, dizziness, confusion, hallucinations, convulsions or transient visual disorders, and advised not to drive or operate machinery if these symptoms occur.