Prednisolone STELLA 5 mg

Rx

Indications

Therapy in conditions when the anti-inflammatory and immunosuppressive effects of glucocorticoids are needed:

• Rheumatoid arthritis,  systemic  lupus  erythematosus,  some  types  of vasculitis,  temporal  arteritis  and  periarteritis  nodosa,  sarcoidosis, bronchial asthma, ulcerative colitis, hemolytic anemia, granulocytopenia and severe allergy conditions including anaphylaxis.
• Treatment against acute leukemia, lymphoma, cancer of the breast and prostate cancer.

Dosage

• The initial adult dosage: 5 – 60 mg daily, depending on the disease being treated, and is usually administered in 2 – 4 divided doses.
• Children: 0.14 – 2 mg/kg daily or 4 – 60 mg/m² daily, administered in 4 divided doses.

Usage

Oral administration.

• Known hypersensitivity to any of the ingredients.
• Serious infection, except septic shock or tuberculous meningitis.
• Viral, fungal, or tubercular skin infection.
• Administration of live virus vaccines.

Prednisolone inhibition of gastric acid secretion and protection of the gastric mucosa.

Common: Insomnia, nervousness, increased appetite, indigestion, hirsutism, diabetes mellitus, arthralgia, cataracts, glaucoma, epistaxis.

Uncommon: Vertigo,  seizures,  psychoses,  pseudotumor cerebri, headache, mood swings, delirium, hallucinations, euphoria, edema, hypertension, acne, skin atrophy, bruising, hyperpigmentation, Cushing of syndrome, pituitary – adrenal axis suppression,  growth  suppression,  glucose  intolerance,  hypokalemia, alkalosis, amenorrhea, sodium and water retention, hyperglycemia, peptic ulcer, nausea, vomiting, abdominal distention, ulcerative esophagitis, pancreatitis, muscle weakness, osteoporosis, fractures, hypersensitivity reactions.

• Patients with osteoporosis, newly established anastomoses (intestine, blood vessel), psychosis, gastric ulcer, duodenal ulcer, diabetes, hypertension, cardiac insufficiency and growing individuals (children).
• Systemic corticosteroids should be used cautiously in the elderly.
• Acute adrenal insufficiency may occur with abrupt withdrawal after long-term therapy or with stress.
• At high doses, interference with vaccination can occur.
• Prednisolone STELLA 5 mg contains lactose. Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose – galactose malabsorption should not take this medicine.
• Pregnancy: Chronic maternal administration of systemic corticosteroids has been associated with a mild decrease in birth weight in human beings. High systemic doses of glucocorticoids may cause small risk for neonatal adrenal hypoplasia.
• Lactation: Caution should be exercised when prednisolone is given to a nursing mother.
• Patients should be aware of how they react to drug before driving or operating machinery.